TESAMORELIN IPAMORELIN 10mg/3mg
$125.00
Tesamorelin is a synthetic peptide composed of 44 amino acids and functions as a growth-hormone-releasing hormone (GHRH) analogue. It is primarily researched for the treatment of HIV-associated lipodystrophy, a condition characterized by abnormal and potentially harmful fat deposition. Additional studies are exploring its potential to support peripheral nerve health, slow the progression of mild cognitive impairment, and reduce visceral fat. Clinical research has shown that tesamorelin can reduce adiposity by nearly 20% in affected populations, and evidence suggests it is approximately four times more effective at reducing fat accumulation than all other currently available therapies combined.
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Tesamorelin
Tesamorelin is a growth hormone-releasing hormone (GHRH) analog that has been shown to increase IGF-1 levels in men by an average of 181 µg/L. It binds to and activates human GHRH receptors with potency comparable to endogenous GHRH. Beyond its growth hormone effects, tesamorelin offers additional benefits, including nootropic effects and triglyceride reduction.
Recent studies have demonstrated that tesamorelin can decrease carotid intima-media thickness (CIMT), visceral adipose tissue (VAT), and C-reactive protein (CRP) levels, without significantly affecting other pituitary hormones or their physiological pathways. Furthermore, research indicates that tesamorelin may improve cognitive function in both healthy older adults and individuals with mild cognitive impairment, who are at elevated risk for progression to Alzheimer’s disease.
Ipamorelin
Ipamorelin is a selective growth hormone (GH) secretagogue and ghrelin receptor agonist. Its ghrelin-stimulating potency is comparable to GHRP-6, but with significantly less effect on appetite. Unlike other GH secretagogues, this pentapeptide does not markedly increase cortisol, acetylcholine, prolactin, or aldosterone levels, which has led to its recognition as the first truly selective GH secretagogue.
When combined with tesamorelin, the two peptides may produce enhanced effects, as each stimulates the growth hormone axis through distinct mechanisms. Together, they synergistically promote the pituitary gland’s production and secretion of endogenous growth hormone at levels comparable to youthful physiology. Research indicates that this combination can improve deep sleep, reduce triglycerides, visceral adipose tissue (VAT), and carotid intima-media thickness (CIMT), enhance cognitive function, and support overall metabolic health.
In preclinical studies, Ipamorelin and Tesamorelin have demonstrated minimal side effects, low oral bioavailability, and excellent subcutaneous bioavailability in mice. Mouse dosage does not directly translate to humans. Both peptides are intended strictly for educational and scientific research purposes and are not approved for human consumption. Purchase and use should be limited to licensed researchers.
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